Population
Single smooth muscle cells (myocytes) isolated from pregnant rat uterus
Design
Preclinical
Authors
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Findings in rat myocytes warrant human validation; leaves open role of L-type currents in clinical uterine disorders.
In pregnant rat uterine myocytes, L-type calcium currents are the primary source of calcium entry during depolarization, which is further amplified by calcium-induced calcium release.
Shmigol et al. (1998) studied this question.
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