Population
Dispersed single smooth muscle cells of the rabbit portal vein
Comparison
Intracellular perfusion with varying… vs Baseline or lower concentrations of…
Design
Preclinical
Authors
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Highlights potential negative feedback in vascular Ca2+ regulation; leaves open translation to human physiology or therapy.
Increases in intracellular calcium dose-dependently inhibit voltage-dependent calcium currents in rabbit portal vein smooth muscle cells, indicating a negative feedback mechanism for calcium regulation.
Ohya et al. (1988) studied this question.
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