Why the study?
Does the 2G or 1G SNP in the MMP1 promoter modify the risk of developing ESCC and GCA in a North Chinese population?
Population
767 individuals from North China, comprising 417 cancer patients and 350 healthy controls.
Comparison
Presence of 2G/2G or 1G/2G genotype in the… vs 1G/1G genotype in the MMP1 promoter
Design
Case-control
Authors
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No association seen in this North Chinese case-control study; leaves open MMP1 polymorphism effects in other populations or larger samples.
Does the 2G or 1G SNP in the MMP1 promoter modify the risk of developing ESCC and GCA in a North Chinese population?
The MMP1 promoter 2G/1G polymorphism is not associated with increased susceptibility to esophageal squamous cell carcinoma or gastric cardiac adenocarcinoma in a North Chinese population.
Jin Xia (2005) studied this question.
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