Comparison of Platelet Indices in Patients with Obstructive Sleep Apnea and Obstructive Lung Diseases + Obstructive Sleep Apnea Syndrome

Introduction:We aimed to observe the changes in platelet activities in patients with obstructive sleep apnea (OSA) and obstructive lung diseases + obstructive sleep apnea (OLDOSA) syndrome.Methods: Adult patients who were followed up with the diagnosis of OSA and OLDOSA syndrome between 06.2018-06.2020 in our clinic were evaluated retrospectively.Changes in platelet indices were investigated.Results: Of the 354 cases included in the study, 240 were male (67.7%) and 114 were female (32.3%).The control group (simple snoring) included 53 patients, the OSA group included 230 patients, and the OLDOSA group included 71 patients.The groups showed similarities in relation to gender (p=0.407).When the mean platelet volume (MPV) and platelet distribution width (PDW) values were evaluated, a significant discrepancy was noted among the different groups (p=0.01,p=0.02, respectively), enhancing coherence.A notable disparity was observed among the groups with regard to cardiovascular diseases (p=0.00). Conclusion:In our study, we found that MPV and PDW values increased in patients with OSA and OLDOSA syndrome compared to the control group in patients with OSA and OLDOSA syndrome.MPV was found to be significantly higher in the OLDOSA group compared to the OSA group.We think that these parameters may be indicators of increased cardiovascular risk in patients with OSA and OLDOSA syndrome.