Increasing the colloid osmotic pressure of cardiopulmonary bypass prime and normothermic blood cardioplegia minimizes myocardial oedema and prevents cardiac dysfunction

6 dogs subjected to normothermic cardiopulmonary bypass

Normothermic cardiopulmonary bypass primed with 6% hetastarch and 1 h of normothermic continuous antegrade blood cardioplegia (4:1 blood:6% hetastarch colloid osmotic pressure 21±2 mmHg) delivered at 50 mmHg perfusion pressure

Myocardial water content, myocardial lymph flow, and left ventricular performance (preload recruitable stroke work)surrogate