Population
Myosin subfragment 1 (S-1)
Design
Preclinical
Authors
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Warrants caution extrapolating myosin inhibition to cardiac function; leaves open relevance in vivo.
The study identifies the specific cysteine residues cross-linked by DBB in myosin subfragment 1 and demonstrates its inhibitory effect on Ca2+-ATPase activity.
Kathleen Ue (1987) studied this question.
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