Population
In vitro protein model (maleimidobenzoyl-G-actin and myosin subfragment 1)
Comparison
Tryptic digestion and EDC-cross-linking vs F-actin and S-1 interaction
Design
Preclinical
Authors
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Distinct MBS-G-actin–S-1 interface; leaves open effects on cardiac sarcomere regulation.
The binding interface between MBS-G-actin and myosin S-1 differs structurally from the physiological F-actin and S-1 interaction.
Tetsu Hozumi (1992) studied this question.
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