Why the study?
Does atrial natriuretic peptide increase coronary flow in open-chest anesthetized dogs?
Population
9 open-chest, anesthetized dogs
Design
Preclinical
Follow-up
Approximately 3 minutes post-infusion
Authors
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ANP coronary effects in dogs merit translational research; leaves open applicability to human coronary physiology or therapy.
Does atrial natriuretic peptide increase coronary flow in open-chest anesthetized dogs?
Intracoronary ANP infusion produces transient, uniform coronary vasodilation without altering systemic hemodynamics in a canine model.
Bauman et al. (1987) studied this question.
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