Why the study?
Does atrial hypertrophy alter regional atrial blood flow and coronary flow reserve during acute atrial fibrillation in a canine model?
Population
Canine model of chronic atrial hypertrophy (n=12) and normal dogs
Comparison
Acute atrial fibrillation vs Normal dogs and control conditions
Design
Preclinical
Authors
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Atrial hypertrophy may reduce coronary flow reserve in AF; extends canine models but leaves human relevance open.
Does atrial hypertrophy alter regional atrial blood flow and coronary flow reserve during acute atrial fibrillation in a canine model?
In a canine model, atrial hypertrophy reduces coronary flow reserve but does not alter the autoregulatory capacity to the hemodynamic stress of atrial fibrillation.
Bauman et al. (1989) studied this question.
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