Population
Canine model of right atrial hypertrophy created by induction of tricuspid regurgitation
Comparison
Induction of tricuspid regurgitation to create… vs Control dogs
Design
Preclinical
Follow-up
1 year
Authors
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Region-specific atrial myocyte hypertrophy in this animal model; hypothesis-generating for human remodeling and requires clinical validation before any practice implications.
The hypertrophic response of atrial myocytes to hemodynamic stress is region-specific and does not require transverse tubule proliferation.
Dolber et al. (1994) studied this question.
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