Why the study?
Does discontinuation of minoxidil resolve isolated exudative pleural effusion in a patient without underlying kidney disease?
Does discontinuation of minoxidil resolve isolated exudative pleural effusion in a patient without underlying kidney disease?
Minoxidil can cause isolated exudative pleural effusion even in patients without underlying kidney disease, which resolves upon drug discontinuation.
Minoxidil discontinuation may resolve isolated exudative pleural effusion; this case report leaves open causality and generalizability.
Recurrent pleural effusions are associated with significant morbidity and mortality. Drug-related reactions causing pleural effusions are not common, but their identification can potentially improve patient outcome. Minoxidil has been implicated in pleuropericardial effusions in patients with chronic kidney disease. The exact mechanism by which pleural effusion occurs is still unclear. We report a case of isolated exudative pleural effusion associated with minoxidil in a patient without underlying kidney disease that almost completely resolved after the drug was discontinued.
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Siddiqui et al. (2010) studied this question.
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