Why the study?
Does nifedipine GITS 20 mg reduce blood pressure and inflammatory markers compared to enalapril 20 mg in patients with mild-to-moderate hypertension?
Population
264 patients with mild-to-moderate hypertension
Comparison
Nifedipine GITS 20 mg for 12 weeks vs Enalapril 20 mg for 12 weeks
Design
RCT, randomized, double-blind
Follow-up
12 weeks
Authors
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Supports flexible agent selection by tolerability or cost; confirms comparable efficacy in this direct RCT comparison.
Does nifedipine GITS 20 mg reduce blood pressure and inflammatory markers compared to enalapril 20 mg in patients with mild-to-moderate hypertension?
Low-dose nifedipine GITS (20 mg) provides similar antihypertensive efficacy to standard-dose enalapril (20 mg) in patients with mild-to-moderate hypertension.
Rosei et al. (2005) studied this question.
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