Why the study?
What is the seroprevalence of poliovirus neutralizing antibodies in children and young women in England?
What is the seroprevalence of poliovirus neutralizing antibodies in children and young women in England?
The study highlights suboptimal poliovirus antibody prevalence in 5-14 year olds and barely satisfactory oral poliovirus vaccine acceptance rates in England during 1972-1974.
May indicate immunity gaps in school-age children; leaves open need for modern serosurveys to guide vaccination policy.
A total of 292 children's sera and 706 antenatal sera from different parts of England were tested for the presence of poliovirus neutralizing antibodies. Little vairation was found between different areas and types of community, but a lower porportion of the 5-14 year old children had antibody than younger children and young adult women. The proportion of the young population with antibody, and the current acceptance rates for oral poliovirus vaccine are barely satisfactory.
No takes yet. Share an insight, caveat, or question.
Mortimer et al. (1975) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: