Why the study?
Does anesthesia alter plasma and kidney ANG II levels differently in normotensive versus ANG II-dependent hypertensive rats?
Does anesthesia alter plasma and kidney ANG II levels differently in normotensive versus ANG II-dependent hypertensive rats?
Anesthesia differentially affects the renin-angiotensin system in normotensive versus hypertensive rat models, suggesting caution when interpreting RAS studies using anesthetized animals.
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Anesthesia may confound RAS measurements in rat models; leaves open translation to conscious animals or clinical anesthesia.
Husková et al. (2006) studied this question.
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