Why the study?
Does absolute VF voltage prior to shock predict defibrillation success in a canine model of ventricular fibrillation?
Does absolute VF voltage prior to shock predict defibrillation success in a canine model of ventricular fibrillation?
The study demonstrates a vulnerable window susceptible to defibrillation in early VF, explaining the sigmoidal dose-response curve through a mathematical model based on excitable cell fluctuation.
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May predict defibrillation success by pre-shock VF voltage in canine VF; leaves open translation to human shock timing or energy selection.
Hsia et al. (1990) studied this question.
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