Why the study?
Heart failure prognosis remains poor with high mortality and reduced quality of life, prompting an assessment of ongoing HF management needs and patient epidemiology in Italian clinics, focusing on cardiac contractility modulation.
What is the epidemiological burden and perceived need for cardiac contractility modulation in Italian heart failure clinics?
What is the epidemiological burden and perceived need for cardiac contractility modulation in Italian heart failure clinics?
There is a perceived gap in treatment options for symptomatic heart failure patients in Italy, with approximately 3% of patients identified as potential candidates for cardiac contractility modulation.
3% of HF patients may qualify for CCM; leaves open broader adoption pending prospective outcome trials.
BACKGROUND: The prognosis for heart failure (HF) patients remains poor, with a high mortality rate, and a marked reduction in quality of life (QOL) and functional status. This study aims to explore the ongoing needs of HF management and the epidemiology of patients followed by Italian HF clinics, with a specific focus on cardiac contractility modulation (CCM). RESEARCH DESIGN AND METHODS: Data from patients admitted to 14 HF outpatients clinics over 4 weeks were collected and compared to the results of a survey open to physicians involved in HF management operating in Italian centers. RESULTS: One hundred and five physicians took part in the survey. Despite 94% of patients receive a regular follow-up every 3-6 months, available therapies are considered insufficient in 30% of cases. Physicians reported a lack of treatment options for 23% of symptomatic patients with reduced ejection fraction (EF) and for 66% of those without reduced EF. Approximately 3% of HF population (two patients per month per HF clinic) meets the criteria for immediate CCM treatment, which is considered a useful option by 15% of survey respondents. CONCLUSIONS: Despite this relatively small percentage, considering total HF population, CCM could potentially benefit numerous HF patients, particularly the elderly, by reducing hospitalizations, improving functional capacity and QOL.
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Ziacchi et al. (2023) studied this question.
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