This case report describes the successful delivery of a normal child in a pregnant woman with a mitral valve replacement managed with warfarin and subsequently heparin.
The case history is presented of a woman aged 38 who received warfarin treatment because of a mitral valve replacement. During the first trimester of pregnancy, her prothrombin time was 20% of normal and kept at 40% until the 38th week of gestation. Then the patient received heparin until a few days after delivery of a normal child.
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Russo et al. (2009) studied this question.
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