Why the study?
Is adenosine a sensitive marker of myocardial ischaemia compared to other metabolites during transient coronary occlusion in patients undergoing PTCA?
Population
18 patients with left coronary obstruction undergoing percutaneous transluminal coronary angioplasty
Comparison
Transient coronary occlusion via balloon… vs Baseline measurements before PTCA (normoxia)
Design
Cohort
Authors
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Adenosine may outperform other metabolites as an ischemia marker during prolonged PTCA occlusion; hypothesis-generating and should not yet change practice.
Is adenosine a sensitive marker of myocardial ischaemia compared to other metabolites during transient coronary occlusion in patients undergoing PTCA?
Adenosine is a highly sensitive marker of myocardial ischemia during transient coronary occlusion, surpassing lactate and hypoxanthine.
Bardenheuer et al. (1994) studied this question.
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