Why the study?
Do low-dose thiazide diuretics reduce cardiovascular events and control blood pressure in elderly patients with isolated systolic hypertension?
Do low-dose thiazide diuretics reduce cardiovascular events and control blood pressure in elderly patients with isolated systolic hypertension?
Low-dose thiazide diuretics are effective, well-tolerated, and the only antihypertensive class shown to reduce cardiovascular events in elderly patients with isolated systolic hypertension.
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Supports low-dose thiazides in elderly ISH; leaves open optimal agent selection and contemporary outcome trials.
William C. Cushman (1993) studied this question.
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