Why the study?
Do different anesthetics (pentobarbital, chloralose, urethan) alter tonic and reflex renal sympathetic nerve activity, arterial blood pressure, and heart rate in cats compared to the awake state?
Population
Conscious cats
Comparison
Administration of pentobarbital sodium… vs Awake state (before administration of anesthetics)
Design
Preclinical
Follow-up
5 hours
Authors
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Anesthetic effects on feline sympathetic activity warrant caution in data interpretation; leaves open optimal agent selection for future studies.
Do different anesthetics (pentobarbital, chloralose, urethan) alter tonic and reflex renal sympathetic nerve activity, arterial blood pressure, and heart rate in cats compared to the awake state?
Different anesthetic agents exert distinct, time-dependent effects on tonic and reflex renal sympathetic nerve activity in feline models, which is critical for interpreting cardiovascular physiological studies under anesthesia.
Matsukawa et al. (1989) studied this question.
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