Why the study?
Are soluble CD40 ligand (sCD40L) levels associated with the presence of coronary artery disease and future cardiovascular events in stable patients undergoing angiography?
Population
909 stable patients undergoing coronary angiography without acute coronary syndrome, matched into three…
Comparison
Serum soluble CD40 ligand (sCD40L) levels vs Lower sCD40L levels / different patient groups
Design
Case-control
Follow-up
1 year
Authors
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Should not alter risk assessment in stable angiography patients; leaves open the paradoxical inverse sCD40L association for prospective validation.
Are soluble CD40 ligand (sCD40L) levels associated with the presence of coronary artery disease and future cardiovascular events in stable patients undergoing angiography?
In stable non-ACS patients undergoing angiography, higher sCD40L levels are paradoxically associated with a decreased risk of CAD and future cardiac events.
Rondina et al. (2007) studied this question.
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