Why the study?
Does intravenous synthetic eledoisin alter systemic and regional hemodynamics in normal subjects?
Does intravenous synthetic eledoisin alter systemic and regional hemodynamics in normal subjects?
Synthetic eledoisin acts as a powerful vasodilator in skin and skeletal muscle, leading to increased cardiac output and transient hypotension in normal subjects.
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No practice change from normal-subject data; leaves open eledoisin's hemodynamic profile for targeted research.
Kontos et al. (1964) studied this question.
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