What question did this study set out to answer?

Evaluate the capability of cardiac cine magnetic resonance imaging to detect and semiquantitatively grade aortic regurgitation compared to Doppler echocardiography.

November 12, 2008Cardiology

Evaluation of Aortic Regurgitation by Cardiac Cine Magnetic Resonance Imaging: Planar Analysis and Comparison to Doppler Echocardiography

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Why the study?

Does cardiac cine MRI accurately assess aortic regurgitation severity compared to Doppler echocardiography in patients with AR?

Population

46 individuals (35 patients with aortic regurgitation and 11 normal volunteers)

Comparison

Cardiac cine magnetic resonance imaging (MRI) vs Pulsed or color flow Doppler echocardiography

Design

Cross-sectional

Authors

GAGerard P. AurigemmaCardiac Imaging NRNathaniel ReichekCardiac Imaging MSMark L. SchieblerUniversity of Wisconsin–Madison

Discussion

Member takes

Implication

May support cine MRI for AR severity when Doppler limited; leaves open prospective validation.

Key Points

Evaluate the capability of cardiac cine magnetic resonance imaging to detect and semiquantitatively grade aortic regurgitation compared to Doppler echocardiography.
Assessed 35 patients with aortic regurgitation and 11 healthy volunteers using cine MRI alongside pulsed Doppler (n = 32) or color flow Doppler (n = 14).
Calculated the ratio of maximal single-plane regurgitant jet area to left ventricular area on cine MRI and categorized severity as mild (<20%), moderate (20–40%), or severe (>40%).
Cine MRI jet-to-ventricle area ratio correlated strongly with pulsed Doppler (r = 0.81) and color flow Doppler (r = 0.88).
Severity classifications matched Doppler determinations in 43 of 46 individuals with no discrepancies exceeding one grade, demonstrating 94% sensitivity and 95% specificity.
Cine MRI directly visualized the regurgitant jet origin at the valve plane in 11 patients.

Structured PICO

Does cardiac cine MRI accurately assess aortic regurgitation severity compared to Doppler echocardiography in patients with AR?

Population

46 individuals (35 patients with aortic regurgitation and 11 normal volunteers)

Intervention

Cardiac cine magnetic resonance imaging (MRI)

Comparator

Pulsed (n=32) or color flow Doppler (n=14) echocardiography

Outcome

Extent of flow disturbance estimated by indexing the size of the maximal, single plane regurgitant jet area (JA) to the left ventricular (LV) areasurrogate

Cardiac cine MRI provides accurate semiquantitative assessment of aortic regurgitation severity comparable to Doppler echocardiography.

Cite This Study

Aurigemma et al. (2008) studied this question.

synapsesocial.com/papers/6a71985d35aa2c282ce2d3ea https://doi.org/10.1159/000174815

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Evaluation of Aortic Regurgitation by Cardiac Cine Magnetic Resonance Imaging: Planar Analysis and Comparison to Doppler Echocardiography

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Evaluation of Aortic Regurgitation by Cardiac Cine Magnetic Resonance Imaging: Planar Analysis and Comparison to Doppler Echocardiography

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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