What question did this study set out to answer?

Assess the efficacy of multilevel cine MR imaging for quantifying aortic regurgitation severity and ventricular dimensions compared to Doppler echocardiography.

April 1, 1989American Journal of Roentgenology

Comparison of cine MR imaging with Doppler echocardiography for the evaluation of aortic regurgitation

View Full Paper

Ask AI

Bookmark

Why the study?

Does cine MR imaging accurately evaluate the severity of aortic regurgitation compared to Doppler echocardiography in patients with aortic regurgitation?

Population

10 normal volunteers and 25 patients with aortic regurgitation documented and graded for severity by Doppler…

Comparison

Multilevel cine MR imaging vs Doppler echocardiography

Design

Cross-sectional

Authors

PPP W PflugfelderUniversity of California, San Francisco JLJS LandzbergUniversity of California, San Francisco MCM M CassidyUniversity of California, San Francisco

Discussion

Member takes

Implication

Diastolic LV signal loss area on cine MRI increases with AR severity; leaves open its accuracy versus Doppler echocardiography for clinical use.

Key Points

Assess the efficacy of multilevel cine MR imaging for quantifying aortic regurgitation severity and ventricular dimensions compared to Doppler echocardiography.
Evaluated 10 normal volunteers and 25 patients with aortic regurgitation graded by Doppler echocardiography (8 mild, 9 moderate, and 8 severe).
Acquired multilevel cine MR images to calculate cardiac chamber volumes, regurgitant fractions, and the area of diastolic signal loss within the left ventricle.
Diastolic left ventricular signal loss area increased with disease severity: 0 cm² in controls, 24 ± 13 cm² in mild, 49 ± 11 cm² in moderate, and 62 ± 20 cm² in severe regurgitation (p < .05 for moderate and severe vs mild).
Calculated regurgitant fraction was 4 ± 7% in healthy controls, 31 ± 8% in mild, 45 ± 11% in moderate, and 56 ± 9% in severe regurgitation (p < .05 for moderate and severe vs mild and normal).
Left ventricular volumes measured by cine MRI correlated strongly with echocardiographic measurements (r = .92, SEE = 30 ml, p < .0001).

Structured PICO

Does cine MR imaging accurately evaluate the severity of aortic regurgitation compared to Doppler echocardiography in patients with aortic regurgitation?

Population

10 normal volunteers and 25 patients with aortic regurgitation documented and graded for severity by Doppler echocardiography (total n=35)

Intervention

Multilevel cine MR imaging

Comparator

Doppler echocardiography

Outcome

Extent of signal loss and regurgitant volume determined from analysis of MR imagessurrogate

Cine MR imaging can provide useful qualitative and quantitative data regarding cardiac dimensions and regurgitant valvular flow that correlates well with Doppler echocardiography in patients with aortic regurgitation.

Cite This Study

Pflugfelder et al. (1989) studied this question.

synapsesocial.com/papers/6a71985d35aa2c282ce2d3ed https://doi.org/10.2214/ajr.152.4.729

View Full Paper

Ask AI

Bookmark

Implication

Diastolic LV signal loss area on cine MRI increases with AR severity; leaves open its accuracy versus Doppler echocardiography for clinical use.

Comparison of cine MR imaging with Doppler echocardiography for the evaluation of aortic regurgitation

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Comparison of cine MR imaging with Doppler echocardiography for the evaluation of aortic regurgitation

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider