Population
Rat aortas (balloon-injured and normal)
Comparison
Balloon injury and ex vivo luminal surface wiping vs Normal (uninjured) rat aortas
Design
Preclinical
Follow-up
24 hours
Authors
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Rapid TF washout may limit post-injury thrombosis in animals; leaves open its contribution to human arterial events.
The rapid release of exposed intimal tissue factor into the circulation may explain the lack of large thrombus formation following arterial injury.
Giesen et al. (2000) studied this question.
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