Key result
No clinical data is available as the provided text only contains journal editorial board information.
Why the study?
Does recombinant tissue factor pathway inhibitor (rTFPI) reduce thrombus formation and neointimal development following repeated balloon injury in a rabbit aorta model?
Population
Rabbit thoracic aortas with previously induced neointima
Comparison
Retrograde bolus injection of recombinant tissue… vs Saline injection
Design
Preclinical
Follow-up
4 weeks
Authors
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No clinical data available; leaves open whether rTFPI reduces restenosis after balloon injury in patients.
Does recombinant tissue factor pathway inhibitor (rTFPI) reduce thrombus formation and neointimal development following repeated balloon injury in a rabbit aorta model?
In a rabbit model of repeated balloon injury, rTFPI administration prevented fibrin-rich thrombus formation and reduced subsequent neointimal growth, suggesting a role for the tissue factor pathway in restenosis.
Asada et al. (1998) studied this question. No clinical data is available as the provided text only contains journal editorial board information.
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