Why the study?
Are central venous pressure and cardiac hemodynamics altered in men with essential hypertension compared to normotensive controls?
Population
76 men, comprising 49 with sustained, uncomplicated essential hypertension and 27 normotensive subjects of…
Comparison
Rapid volume expansion using iso-oncotic dextran… vs Normotensive subjects
Design
Cross-sectional
Authors
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Should not yet change hypertension management; leaves open whether reduced venous compliance drives elevated central venous pressure.
Are central venous pressure and cardiac hemodynamics altered in men with essential hypertension compared to normotensive controls?
Essential hypertension is associated with increased central venous pressure, likely due to decreased compliance of the venous bed or left ventricle rather than hypervolemia or altered cardiac pump function.
London et al. (1985) studied this question.
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