Why the study?
Does oral propranolol improve platelet aggregability and exercise tolerance in patients with severe but stable angina pectoris?
Population
19 patients with severe but stable angina pectoris who had positive ECG response to exercise on a bicycle…
Comparison
Oral propranolol 80 mg/day vs Placebo
Design
RCT, Randomized into placebo (n = 9) and propranolol (n = 10) treatment groups
Authors
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Supports propranolol in severe stable angina; extends evidence by linking platelet normalization to exercise gains.
Does oral propranolol improve platelet aggregability and exercise tolerance in patients with severe but stable angina pectoris?
Oral propranolol normalizes increased in vitro platelet aggregability and significantly improves exercise tolerance in patients with severe but stable angina pectoris.
Frishman et al. (1974) studied this question.
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