Why the study?
Does intravenous morphine cause different cardiac arrhythmias depending on whether the right or left vagus nerve is removed in dogs?
Population
12 dogs (6 with right vagus nerve removed aseptically, 6 with left vagus nerve removed)
Comparison
Intravenous morphine injection vs Morphine injection before operation and…
Design
Preclinical
Authors
Loading...
Should not yet change practice; leaves open vagal asymmetry in morphine-related arrhythmias for human investigation.
Does intravenous morphine cause different cardiac arrhythmias depending on whether the right or left vagus nerve is removed in dogs?
Morphine-induced cardiac arrhythmias in dogs are mediated differently by the right and left vagus nerves, with right vagus removal leading to profound bradycardia and ectopic ventricular rhythms.
Alfred E. Cohn (1913) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: