Why the study?
Does trandolapril 2 mg once daily reduce clinic and 24-h blood pressures in mild and moderate hypertensive patients?
Population
62 mild and moderate hypertensive patients
Comparison
Trandolapril 2 mg once daily for 6 weeks vs Placebo for 6 weeks
Design
RCT, double-blind
Follow-up
6 weeks
Authors
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Trandolapril 2 mg once daily supports 24-hour BP control in mild-moderate hypertension; confirms sustained ACE-inhibitor efficacy in RCTs.
Does trandolapril 2 mg once daily reduce clinic and 24-h blood pressures in mild and moderate hypertensive patients?
Trandolapril 2 mg once daily effectively reduces both clinic and 24-hour ambulatory blood pressure in patients with mild to moderate hypertension.
Ravogli et al. (1994) studied this question.
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