Key result
Left ventricular remodeling was associated with an increased risk of MACE in patients with incomplete revascularization (HR 3.22; 95% CI 1.19-8.71; p=0.002), but not with complete revascularization.
Why the study?
The study sought to identify factors related to left ventricular remodeling and evaluate its prognostic impact in STEMI patients with multivessel disease treated with complete versus incomplete revascularization.
Does left ventricular remodeling worsen clinical outcomes in patients with STEMI and multivessel disease depending on the completeness of revascularization?
Population
262 STEMI patients with multivessel disease without LVR at presentation
Comparison
Complete revascularization vs incomplete revascularization according to LVR status
Follow-up
Between 1 month and 1 year
Authors
Loading...
LV remodeling may flag higher MACE risk after incomplete revascularization; hypothesis-generating for whether complete revascularization modifies this association.
Cohort (n=262)
Does left ventricular remodeling worsen clinical outcomes in patients with STEMI and multivessel disease depending on the completeness of revascularization?
Hazard Ratio: 3.22 (95% CI 1.19–8.71)
p-value: p=0.002
Left ventricular remodeling within the first year after PCI for STEMI with multivessel disease is associated with worse outcomes in patients with incomplete revascularization, but this risk is mitigated by complete revascularization.
Kim et al. (2022) conducted a cohort in ST-elevation myocardial infarction and multivessel disease (n=262). Left ventricular remodeling (LVR) vs. No left ventricular remodeling was evaluated on Composite of all-cause death, MI, and heart failure (MACE) (HR 3.22, 95% CI 1.19-8.71, p=0.002). Left ventricular remodeling was associated with an increased risk of MACE in patients with incomplete revascularization (HR 3.22; 95% CI 1.19-8.71; p=0.002), but not with complete revascularization.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: