June 1, 1962Acta Physiologica Scandinavica

Lactic Acid Production and Adrenaline Reversal in Experiments on Isolated Smooth Muscle

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Population

Isolated muscle preparations from rabbit stomach

Design

Preclinical

Authors

EMElla Mohme‐LundholmLinköping University

Discussion

Member takes

Implication

Dibenamine selectively blocks adrenergic contraction in gastric smooth muscle; leaves open whether metabolic effects are receptor-independent.

Structured PICO

Population

Isolated muscle preparations from rabbit stomach

Intervention

Adrenaline before and after treatment with dibenamine

Outcome

Muscle contraction/relaxation and lactic acid contentsurrogate

Dibenamine selectively inhibits the contracting effect of adrenaline on rabbit stomach smooth muscle without altering its stimulation of lactic acid production.

Cite This Study

Ella Mohme‐Lundholm (1962) studied this question.

synapsesocial.com/papers/6a71cb8a31a3df824329d181 https://doi.org/10.1111/j.1748-1716.1962.tb02435.x

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Implication

Dibenamine selectively blocks adrenergic contraction in gastric smooth muscle; leaves open whether metabolic effects are receptor-independent.