July 1, 1996Diabetes
Diabetic Dyslipidemia: Basic Mechanisms Underlying the Common Hypertriglyceridemia and Low HDL Cholesterol Levels
Population
Patients with diabetes, particularly non-insulin-dependent diabetes mellitus, with hypertriglyceridemia and…
Design
Review
Authors
Discussion
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Member takes
Implication
Highlights free fatty acid flux in diabetic dyslipidemia; leaves open whether targeting it improves outcomes.
Structured PICO
P
Population
Patients with diabetes, particularly non-insulin-dependent diabetes mellitus (NIDDM), with hypertriglyceridemia and low HDL cholesterol
The review highlights that increased free fatty acid flux to the liver in insulin-resistant states is the primary driver of elevated triglycerides and low HDL cholesterol in diabetic patients.
Cite This Study
Henry N. Ginsberg (1996) studied this question.