Population
Mammalian cells and SV40 genome segments
Design
Preclinical
Authors
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Host cell recombination of SV40 segments occurs without viral proteins; leaves open its contribution to viral persistence or oncogenesis in vivo.
Demonstrates that mammalian host cells possess intrinsic functions capable of recombining genetic elements like SV40 genome segments without viral proteins.
Upcroft et al. (1980) studied this question.
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