Why the study?
Does guideline-adherent antithrombotic treatment improve outcomes in high-risk patients with atrial fibrillation?
Does guideline-adherent antithrombotic treatment improve outcomes in high-risk patients with atrial fibrillation?
Adherence to ESC guidelines for antithrombotic treatment in atrial fibrillation significantly reduces mortality, thromboembolism, and bleeding compared to under- or over-treatment.
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Guideline-adherent antithrombotic therapy was associated with lower TE and bleeding in high-risk AF; leaves open causal effects in randomized settings.
Lip et al. (2015) studied this question.
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