January 1, 1992American Review of Respiratory Disease

At 3 months, VO2max was 46% of predicted for SLT and 50% of predicted for DLT recipients, with no significant improvement when retested 1 to 2 years after transplant.

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Why the study?

Does exercise capacity improve over time in single and double lung transplant recipients?

Population

13 lung transplant recipients, including 6 single-lung and 7 double-lung recipients.

Design

Cohort

Follow-up

1 to 2 years

Authors

TWTrevor J. Williams GPG. Alexander Patterson PMPatricia McClean

Discussion

Member takes

Overview

Persistent limitation up to 2 years post-transplant warrants caution in expectations; leaves open whether rehabilitation targets deconditioning in recipients.

Structured PICO

Does exercise capacity improve over time in single and double lung transplant recipients?

Population

13 lung transplant recipients, including 6 single-lung (SLT) (5 males, 1 female; age 50.7 +/- 4.4) and 7 double-lung (DLT) (3 males, 4 females; age 37.3 +/- 6.7) recipients.

Intervention

Maximal exercise testing (Stage 1 exercise test) early (3 months) and late (1 to 2 years) following transplantation.

Outcome

Exercise capacity (work rates and VO2max)surrogate

Considerable exercise limitation persists up to 2 years after single or double lung transplantation, suggesting chronic muscle deconditioning rather than ventilatory limitation.

Cite This Study

Williams et al. (1992) studied this question.

synapsesocial.com/papers/6a71e7ffa7fbea1e4408891e https://doi.org/10.1164/ajrccm/145.1.101

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January 1, 1992American Review of Respiratory Disease

At 3 months, VO2max was 46% of predicted for SLT and 50% of predicted for DLT recipients, with no significant improvement when retested 1 to 2 years after transplant.

View Full Paper

Ask AI

Bookmark

Why the study?

Does exercise capacity improve over time in single and double lung transplant recipients?

Population

13 lung transplant recipients, including 6 single-lung and 7 double-lung recipients.

Design

Cohort

Follow-up

1 to 2 years

Authors

TWTrevor J. Williams GPG. Alexander Patterson PMPatricia McClean

Discussion

Member takes

Overview

Persistent limitation up to 2 years post-transplant warrants caution in expectations; leaves open whether rehabilitation targets deconditioning in recipients.

Structured PICO

Does exercise capacity improve over time in single and double lung transplant recipients?

Population

13 lung transplant recipients, including 6 single-lung (SLT) (5 males, 1 female; age 50.7 +/- 4.4) and 7 double-lung (DLT) (3 males, 4 females; age 37.3 +/- 6.7) recipients.

Intervention

Maximal exercise testing (Stage 1 exercise test) early (3 months) and late (1 to 2 years) following transplantation.

Outcome

Exercise capacity (work rates and VO2max)surrogate

Considerable exercise limitation persists up to 2 years after single or double lung transplantation, suggesting chronic muscle deconditioning rather than ventilatory limitation.

Cite This Study

Williams et al. (1992) studied this question.

synapsesocial.com/papers/6a71e7ffa7fbea1e4408891e https://doi.org/10.1164/ajrccm/145.1.101

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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