Why the study?
Does MRI with Gd-DOTA contrast enhancement accurately detect and grade cardiac allograft rejection in transplant recipients?
Population
46 participants. Patients were grouped by histological findings: no rejection, grade 1 rejection, and grade…
Comparison
MRI with intravenous gadolinium… vs Comparison across histological rejection grades
Design
Cross-sectional
Authors
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May support noninvasive MRI monitoring of cardiac allograft rejection; hypothesis-generating and should not yet change biopsy-based practice.
Does MRI with Gd-DOTA contrast enhancement accurately detect and grade cardiac allograft rejection in transplant recipients?
MRI with Gd-DOTA contrast enhancement can distinguish between cardiac transplant recipients with and without histological rejection based on regional myocardial enhancement.
Mousseaux et al. (1993) studied this question.
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