Why the study?
Do spontaneously occurring MSNA bursts decrease conduit artery diameter on a beat-by-beat basis during rest in healthy young men?
Population
20 young men, mean age 25 ± 1 yr, height 177 ± 1 cm, weight 77 ± 1 kg. Exclusion criteria: hypertension…
Comparison
Observation of spontaneously occurring muscle… vs Cardiac cycles without MSNA bursts and white…
Design
Other
Follow-up
20 minutes
Authors
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MSNA bursts may passively dilate conduit arteries via pressor effects; leaves open direct sympathetic control of larger vessels in health and disease.
Do spontaneously occurring MSNA bursts decrease conduit artery diameter on a beat-by-beat basis during rest in healthy young men?
Spontaneously occurring MSNA bursts do not directly cause local vasoconstriction in conduit arteries, but rather induce a systemic pressor response that passively increases conduit artery diameter.
Fairfax et al. (2013) studied this question.
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