Why the study?
Does graded infusion of noradrenaline affect plasma noradrenaline levels and clearance differently in normal subjects compared to essential hypertensives?
Does graded infusion of noradrenaline affect plasma noradrenaline levels and clearance differently in normal subjects compared to essential hypertensives?
The study provides no evidence that altered noradrenaline metabolism predisposes to elevated noradrenaline levels in essential hypertension.
No takes yet. Share an insight, caveat, or question.
Does not support altered NA metabolism in essential hypertension; leaves open sympathetic mechanisms and requires confirmation.
Gordon et al. (1987) studied this question.
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