Why the study?
Do higher HbA1c levels increase the risk of all-cause and cardiovascular mortality in a general Japanese population free of previous CVD?
Population
7,120 participants from the general Japanese population, free of previous cardiovascular disease.
Comparison
HbA1c levels. vs HbA1c <5.0%
Design
Cohort
Follow-up
15 years
Authors
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Extends graded CVD mortality link with rising HbA1c to CVD-free East Asians; confirms Western pattern but leaves causality and practice change open.
Do higher HbA1c levels increase the risk of all-cause and cardiovascular mortality in a general Japanese population free of previous CVD?
High HbA1c levels are associated with a graded, continuous increase in the risk of all-cause and cardiovascular mortality in the general East Asian population, similar to findings in Western populations.
Sakurai et al. (2013) studied this question.
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