Population
Patients with uncomplicated isolated systolic hypertension (ISH) and matched normotensive controls
Design
Case-control
Authors
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Increased arterial compliance in ISH may compensate for aortic changes; hypothesis-generating and should not yet change practice.
Isolated systolic hypertension is associated with changes across the entire peripheral vascular bed, including increased small artery compliance that may partially compensate for decreased aortic buffering.
Muntinga et al. (2000) studied this question.
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