Why the study?
Fontan patients may have abnormal diastolic function, but it is poorly characterized using conventional echocardiography.
Are atrial and ventricular diastolic strain parameters altered in pediatric Fontan patients compared to healthy controls, and do they differ by ventricular morphology?
Population
50 pediatric Fontan patients and 50 healthy controls
Comparison
Fontan patients vs controls, and RV type vs LV type Fontan
Design
Single-institution cross-sectional study
Authors
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Diastolic strain differences in Fontan patients are hypothesis-generating; leaves open their prognostic value before clinical adoption.
Are atrial and ventricular diastolic strain parameters altered in pediatric Fontan patients compared to healthy controls, and do they differ by ventricular morphology?
Pediatric Fontan patients exhibit significantly altered atrial and diastolic strain parameters compared to healthy controls, with more pronounced derangements in those with right ventricular morphology.
Loar et al. (2025) studied this question.
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