July 1, 1967The Journal of Pathology and BacteriologyOpen Access

The mechanism of the delayed prolonged phase of increased vascular permeability in mild thermal injury in the rat

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Population

15 adult rhesus monkeys

Design

Preclinical

Follow-up

2 years

Authors

JHJ. V. HurleyThe University of Melbourne KHKathryn N. HamThe University of Melbourne GRG. B. RyanThe University of Melbourne

Discussion

Member takes

Implication

Rhesus monkeys may model human serological responses to endemic mycoses; leaves open clinical translation.

Structured PICO

Population

15 adult rhesus monkeys

Intervention

Inoculation with nonviable Histoplasma capsulatum, Blastomyces dermatitidis, or Coccidioides immitis

Outcome

Serological patterns measured by antibody assays (complement-fixation test, latex-agglutination test, immunodiffusion test, coccidioidin-precipitin test)surrogate

Rhesus monkeys provide a comparable serological model to human patients for studying immune responses to Histoplasma, Blastomyces, and Coccidioides.

Cite This Study

Hurley et al. (1967) studied this question.

synapsesocial.com/papers/6a7204b4febe604dd70a663a https://doi.org/10.1002/path.1700940102

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The mechanism of the delayed prolonged phase of increased vascular permeability in mild thermal injury in the rat

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The mechanism of the delayed prolonged phase of increased vascular permeability in mild thermal injury in the rat

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider