Why the study?
Does oral diazoxide alter insulin binding and sensitivity in normal subjects and patients with NIDDM?
Does oral diazoxide alter insulin binding and sensitivity in normal subjects and patients with NIDDM?
Diazoxide induces post-receptor insulin resistance in patients with NIDDM without affecting insulin binding, suggesting its utility as a tool for studying post-receptor binding events.
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Diazoxide may induce post-receptor insulin resistance in NIDDM; leaves open its utility as a research tool for insulin signaling studies.
Olczak et al. (1986) studied this question.
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