Why the study?
What is the mechanism of diazoxide-induced hyperglycemia in humans?
What is the mechanism of diazoxide-induced hyperglycemia in humans?
Diazoxide induces hyperglycemia through mechanisms likely involving endogenous sympathetic stimulation, characterized by decreased insulin and increased free fatty acids.
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Diazoxide hyperglycemia may involve sympathetic stimulation; hypothesis-generating for mechanisms but should not yet change practice.
Graber et al. (1966) studied this question.
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