Why the study?
Is the presence of a sinking pre-beta lipoprotein associated with an increased risk of coronary heart disease in Japanese-American men?
Population
1,854 men of Japanese ancestry, aged 50-72 years, in Honolulu, Hawaii.
Comparison
Presence of a 'sinking' pre-beta lipoprotein. vs Men without the 'sinking' pre-beta lipoprotein…
Design
Cross-sectional
Authors
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Sinking pre-beta lipoprotein was associated with higher CHD prevalence independent of LDL; hypothesis-generating for prospective risk prediction.
Is the presence of a sinking pre-beta lipoprotein associated with an increased risk of coronary heart disease in Japanese-American men?
The presence of a sinking pre-beta lipoprotein (a likely marker for Lp antigen) is associated with a higher prevalence of coronary heart disease, independent of LDL levels.
Rhoads et al. (1978) studied this question.
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