Population
Conscious rats
Design
Preclinical
Authors
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Should not change clinical glucose flux assessment; extends quantitative 13C NMR analysis to conscious rat muscle under hyperglycemia.
In vivo 13C NMR spectroscopy can quantitatively determine intramuscular glucose metabolism fluxes in conscious rats, demonstrating that pyruvate carboxylation is the major pathway for anaplerosis under hyperglycemia-hyperinsulinemia.
Jucker et al. (1997) studied this question.