Population
90 untreated patients with uncomplicated essential hypertension, mean age 58.7 +/- 12.9 years.
Design
Cross-sectional
Authors
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Augmentation index may flag early vascular changes in younger hypertensives with nondipping; hypothesis-generating and requires prospective validation before clinical use.
Augmentation index of the radial pressure waveform is associated with abnormal diurnal blood pressure variation in untreated hypertensive patients aged 60 years or younger, suggesting its utility as an early marker of vascular stiffness.
Shinohata et al. (2008) studied this question.
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