Why the study?
The underlying pathomechanism of diabetic cardiomyopathy is only partially understood, and summarizing animal models according to pathomechanisms may broaden mechanistic understanding and facilitate identification of therapeutic targets.
This review summarizes the pathomechanisms of diabetic cardiomyopathy and the various rodent models used to study them, providing a framework for identifying new therapeutic targets.
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DiaCM mechanisms remain incompletely defined; leaves open targeted studies before clinical translation.
Lee et al. (2021) studied this question.
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