Population
Reovirus outer capsid protein sigma 3
Design
Preclinical
Authors
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May guide antiviral design targeting sigma 3 domains; leaves open in vivo roles in transcription.
The reovirus outer capsid protein sigma 3 has distinct binding sites for zinc and dsRNA, which may be important for its regulatory effects on viral and host cell transcription and translation.
Schiff et al. (1988) studied this question.
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